Luminaries in the music industry have expressed their grief after the death of rapper Nipsey Hussle, who was shot dead in Los Angeles earlier today. 

Hussle, 33, was targeted outside a clothing store he owned in south LA around 3:20pm local time.

The musician, whose latest record Victory Lap was nominated for Best Rap Album at the 2019 Grammy Awards, was transported to hospital where he was pronounced deceased.

Two other men were hospitalised and are reportedly in stable conditions, a Los Angeles Police Department spokesperson said.

The suspected shooter remains at large.

News of his death prompted an impassioned response from his contemporaries and former collaborators, who praised him for his artistic skills and commitment to uplifting his community.

John Legend and Drake both spoke about their time working with Hussle and his sense of integrity.

Hussle is survived by his two children and his partner, Lauren London.

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